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Human Photon Dynamics Determined by Using Photon Count Statistics

E.P.A. van Wijk, J. van der Greef, R. van Wijk
08/2013

Analysis of oligosaccharides in lignocellulosic biomass hydrolysates by high-performance anion-exchange chromatography couples with mass spectrometry (HPAEC-MS)
Y. Zha, L. Coulier, R. Bas, P.J. Punt
04/2013

Exometabolomics Appraches in Studying the Application of Lignocellulosic Biomass as Fermentation Feedstock
Y. Zha, P.J. Punt
02/2013

Automated Pipeline For De Novo Metabolite Identification Using Mass-Spectrometry-Based Metabolomics
J.E. Peironcely, M. Rojas-Chertó, A. Tas, R.J. Vreeken, T. Reijmers, L. Coulier, T. Hankemeier
01/2013

Pervaporation of ethanol from lignocellulosic fermentation broth
S.S. Gaykawad, Y. Zha, P.J. Punt, J.W. van Groenestijn, L.A.M. van der Wielen, A.J.J. Straathof
12/2012

Metabolic and transcriptomic changes induced in Arabidopsis by the rhizobacterium Pseudomonas fluorescens SS101
J.E. van de Mortel, R.C.H. de Vos, E. Dekkers, A. Pineda, L. Guillod, K. Bouwmeester, J.J.A. van Loon, M. Dicke, J.M. Raaijmakers
12/2012

Increase in short‐chain ceramides correlates with an altered lipid organization and decreased barrier function in atopic eczema patients
M. Janssens, J. van Smeden, G.S. Gooris, W. Bras, G. Portale, P.J. Caspers, R.J. Vreeken, T. Hankemeier, S. Kezic, R. Wolterbeek, A.P. Lavrijsen, J.A. Bouwstra
12/2012

Gut microbial metabolism of polyphenols from black tea and red wine/grape juice is source-specific and colon-region dependent
F.A. van Dorsten, S. Peters, G. Gross, V. Gomez-Roldan, M. Klinkenberg, R.C.H. de Vos, E.E. Vaughan, J.P. van Duynhoven, S. Possemiers, T. van de Wiele, D.M. Jacobs
11/2012

Ultra-weak photon emission from organisms
E. van Wijk, Y. Yan
10/2012

Feasibility of electroextraction as versatile sample preconcentration for fast and sensitive analysis of urine metabolites, demonstrated on acylcarnitines
P.W. Lindenburg, U.R. Tjaden, J. van der Greef, T. Hankemeier
10/2012

OMG: Open Molecule Generator
J.E. Peironcely, M. Rojas-Chertó, D. Fichera, T. Reijmers, L. Coulier, J.-L. Faulon, T. Hankemeier
09/2012

Characterization of Rheumatoid Arthritis Subtypes Using Symptom Profiles, Clinical Chemistry and Metabolomics Measurements
H.A. van Wietmarschen, W. Dai, A.J. van der Kooij, T.H. Reijmers, Y. Schroën, M. Wang, Z. Xu, X. Wang, H. Kong, G. Xu, T. Hankemeier, J.J. Meulman, J. van der Greef
09/2012

Tunable ionic mobility filter for depletion zone isotachophoresis
J. Quist, P. Vulto, H.J. van der Linden, T. Hankemeier
09/2012

Generic framework for high-dimensional fixed-effects ANOVA
A.K. Smilde, M.E. Timmerman, M.M.W.B. Hendriks, J.J. Jansen, H.C. Hoefsloot
09/2012

Fragmentation trees for the structural characterisation of metabolites
P.T. Kasper, M. Rojas-Chertó, R. Mistrik, T. Reijmers, T. Hankemeier, R.J. Vreeken
08/2012

MSClust: a tool for unsupervised mass spectra extraction of chromatography-mass spectrometry ion-wise aligned data
Y.M. Tikunov, S. Laptenok, R.D. Hall, A. Bovy, R.C.H. de Vos
08/2012

Instrument and process independent binning and baseline correction methods for liquid chromatography-high resolution-mass spectrometry deconvolution
S. Krishnan, J.T. Vogels, L. Coulier, R.C. Bas, M.M.W.B. Hendriks, T. Hankemeier, U. Thissen
08/2012

Chemical identification strategies using liquid chromatography-photodiode array-solid-phase extraction-nuclear magnetic resonance/mass spectrometry
S. Moco, J. Vervoort
08/2012

On-line large-volume electroextraction coupled to liquid chromatography-mass spectrometry to improve detection of peptides
P.W. Lindenburg, F.W.A. Tempels, U.R. Tjaden, J. van der Greef, T. Hankemeier
08/2012

Limits of miniaturization: assessing ITP performance in sub-micron and nanochannels
K.G.H. Janssen, J.J. Li, H.T. Hoang, P. Vulto, R. van den Berg, H.S. Overkleeft, J.C.T. Eijkel, N.R. Tas, H.J. van der Linden, T. Hankemeier
08/2012

Structural elucidation and quantification of phenolic conjugates present in human urine after tea intake
Van der Hooft, J.J.J., De Vos, C.H., Mihaleva, V., Bino, R.J., Ridder, L., De Roo, N., Jacobs, D.M., Van Duynhoven, J.P.M., Vervoort, J.
07/2012

MetiTree: a web application to organize and process high-resolution multi-stage mass spectometry metabolomics data
M. Rojas-Chertó, M. van Vliet, J.E. Peironcely, R. van Doorn, M. Kooyman, T. te Beek, M.A. van Driel, T. Hankemeier, T. Reijmers
07/2012

Preparation and Evaluation of Lignocellulosic Biomass Hydrolysates for Growth by Ethanologenic Yeasts
Y. Zha, R. Slomp, J. van Groenestijn, P.J. Punt
07/2012

Topology of Transcriptional Regulatory Networks: Testing and Improving
D. Hasdemir, G.J. Smits, J.A. Westerhuis, A.K. Smilde
07/2012

Metabolite Space of Rheumatoid Arthritis
H. van Wietmarschen, J. van der Greef
07/2012

Solid phase micro-extraction GC-MS analysis of natural volatile components in melon and rice
H.A. Verhoeven, H. Jonker, R.C.H. de Vos, R.D. Hall
06/2012

Individual differences in metabolomics: individualised responses and between-metabolite relationships
J.J. Jansen, E. Szymańska, H.C. Hoefsloot, A.K. Smilde
06/2012

Inferring differences in the distribution of reaction rates across conditions
D.M. Hendrickx, H.C.J. Hoefsloot, M.M.W.B. Hendriks, D.J. Vis, A.B. Canelas, B. Teusink, A.K. Smilde
05/2012

Metabolite Identification Using Automated Comparison of High-Resolution Multistage Mass Spectral Trees
M. Rojas-Cherto, J.E. Peironcely, P.T. Kasper, J.J.J. van der Hooft, R.C.H. de Vos, R.J. Vreeken, T. Hankemeier, T. Reijmers
05/2012

Genetic analysis of metabolites in apple fruits indicates an mQTL hotspot for phenolic compounds on linkage group 16
S.A. Khan, P.Y. Chibon, R.C.H. de Vos, B.A. Schipper, E. Walraven, J. Beekwilder, T. van Dijk, R. Finkers, R.G. Visser, E.W. van de Weg, A. Bovy, A. Cestaro, R. Velasco, E. Jacobsen, H.J. Schouten
05/2012

A strategy for fast structural elucidation of metabolites in small volume plant extracts using automated MS-guided LC-MS-SPE-NMR
Van der Hooft, J.J.J., Mihaleva, V., de Vos, R.C.H., Bino, R.J., Vervoort, J.
03/2012

Metabolomics of cerebrospinal fluid reveals changes in the central nervous system metabolism in a rat model of multiple sclerosis
Marek J. Noga, Adrie Dane, Shanna Shi, Amos Attali, Hans van Aken, Ernst Suidgeest, Tinka Tuinstra, Bas Muilwijk, Leon Coulier, Theo Luider, Theo H. Reijmers, Rob J. Vreeken, Thomas Hankemeier
03/2012

Spectral trees as a robust annotation tool in LC-MS based metabolomics
Van der Hooft, J.J.J., Vervoort, J., Bino, R.J., Beekwilder, J., de Vos, R.C.H.
03/2012

High-performance Liquid Chromatography (HPLC)-Mass Spectrometry (MS) analysis of plant metabolites in Brassicaceae.
De Vos, R.C.H., Schipper, B., Hall, R.D.
03/2012

Global test for metabolic pathway differences between conditions
D.M. Hendrickx, H.C.J. Hoefsloot, M.M.W.B. Hendriks, A.B. Canelas, A.K. Smilde
03/2012

Detecting Regulatory Mechanisms in Endocrine Time Series Measurements

D.J. Vis, J.A. Westerhuis, H.C.J. Hoefsloot, F. Roelfsema, M.M.W.B. Hendriks, A.K. Smilde
03/2012

Urine metabolomics combined with the personalized diagnosis guided by Chinese medicine reveals subtypes of pre-diabetes
H. Wei, W. Pasman, C. Rubingh, S. Wopereis, M. Tienstra, J. Schroen, M. Wang, E. Verheij, J. van der Greef
03/2012

Nano-slit electrospray emitters fabricated by a micro- to nanofluidic via technology
M. Dijkstra, J.W. Berenschot, M.J. de Boer, H.J. van der Linden, T. Hankemeier, T.S.J. Lammerink, R.J. Wiegerink, M. Elwenspoek, N.R. Tas
03/2012

Discovery of early-stage biomarkers for diabetic kidney disease using ms-based metabolomics (FinnDiane study)
F.M. van der Kloet, F.W. Tempels, N. Ismail, R. van der Heijden, P.T. Kasper, M. Rojas-Cherto, R. van Doorn, G. Spijksma, M. Koek, J. van der Greef, V.P. Mäkinen, C. Forsblom, H. Holthöfer, P.H. Groop, T. Reijmers, T. Hankemeier
02/2012

Transportomics: screening for substrates of ABC transporters in body fluids using vesicular transport assays
P. Krumpochova, S. Sapthu, J.F. Brouwers, M. de Haas, R.C.H. de Vos, P. Borst, K. van de Wetering
02/2012

Enrichment of viable bacteria in a micro-volume by free-flow electrophoresis
S. Podszun, P. Vulto, H. Heinz, S. Hakenberg, C. Hermann, T. Hankemeier, G.A. Urban
02/2012

Lipidomics Reveals Multiple Pathway Effects of a Multi-Components Preparation on Lipid Biochemistry in ApoE*3Leiden.CETP Mice
H. Wei, C. Hu, M. Wang, A.M. van den Hoek, T.H. Reijmers, S. Wopereis, J. Bouwman, R. Ramaker, H.A.A.J. Korthout, M. Vennik, T. Hankemeier, L.M. Havekes, R.F. Witkamp, E.R. Verheij, G. Xu, J. van der Greef
01/2012

Structural Annotation and Elucidation of Conjugated Phenolic Compounds in Black, Green, and White Tea Extracts
Justin J. J. van der Hooft, Moktar Akerm, Fatma Yelda Ünlü, Velitchka Mihaleva, Victoria Gomez Roldan, Raoul J. Bino, Ric C. H. de Vos, and Jacques Vervoort
01/2012

Inhibitory compounds in lignocellulosic biomass hydrolysates during hydrolysate fermentation processes
Y. Zha, B. Muilwijk, L. Coulier, P.J. Punt
01/2012

High-performance liquid chromatography-mass spectrometry analysis of plant metabolites in brassicaceae
R.C.H. de Vos, B. Schipper, R.D. Hall
01/2012

An efficient hydrophilic interaction liquid chromatography separation of 7 phospholipid classes based on a diol column
C. Zhu, A. Dane, G. Spijksma, M. Wang, J. van der Greef, G.A. Luo, T. Hankemeier, R.J. Vreeken
01/2012

Understanding and Classifying Metabolite Space and Metabolite-Likeness
Julio E. Peironcely, Theo Reijmers, Leon Coulier, Andreas Bender, Thomas Hankemeier
12/2011

A lipidomic analysis approach to evaluate the response to cholesterol-lowering food intake
E. Szymanska, F.A. van Dorsten, J. Troost, I. Paliukhovich, E. van Velzen, M. Hendriks, E.A. Trautwein, J.P.M. van Duynhoven, R.J. Vreeken, A.K. Smilde
12/2011

Photon Counts Statistics in Leukocyte Cell
E. van Wijk, J. van der Greef, R. van Wijk
12/2011

Perspective: All systems go
Jan van der Greef
12/2011

Data-processing strategies for metabolomics studies
Margriet M.W.B. Hendriks, Fred A. van Eeuwijk, Renger H. Jellema, Johan A. Westerhuis, Theo H. Reijmers, Huub C.J. Hoefsloot, Age K. Smilde
11/2011

Tracy-Widom statistic for the largest eigenvalue of autoscaled real matrices
E. Saccenti, J. A. Westerhuis, A. K. Smilde and M. M. W. B. Hendriks
11/2011

A genomics and multi-platform metabolomics approach to identify new traits of rice quality in traditional and improved varieties
M.N. Calingacion, C. Boualaphanh, V. D. Daygon, R. Anacleto, R. Sackville Hamilton, B. Biais, C. Deborde, M. Maucourt, A. Moing, R. Mumm, R.C.H. de Vos, A. Erban, J. Kopka, T. H. Hansen, K.H. Laursen, J.K. Schjoerring, R.D. Hall, M.A. Fitzgerald
10/2011

Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of platinum-Induced Fatty Acids
Jeanine M.L. Roodhart, Laura G.M. Daenen, Edwin C.A. Stiger, Henk-Jan Prins, Johan Gerrits, Julia M. Houthuijzen, Marije G. Gerritsen, Henk S. Schipper, Marieke J.G. Backer, Miranda van Amersfoort, Joost S.P. Vermaat, Petra Moerer, Kenji Ishihara, Eric Kalkhoven, Jos H. Beijnen, Patrick W.B. Derksen, Rene H. Medema, Anton C. Martens, Arjan B. Brenkman and Emile E. Voest
09/2011

Double-check: validation of diagnostic statistics for PLS-DA models in metabolomics studies
E. Szymanska, E. Saccenti, A.K. Smilde, J.A. Westerhuis
08/2011

Single-Electrolyte isotachophoresis Using a Nanochannel-Induced Depletion Zone
Jos Quist*, Kjeld G.H. Janssen* (equally contributing), Paul Vulto, Thomas Hankemeier, Heiko J. van der Linden
08/2011

Linking biological activity with herbal constituents by systems biology-based approaches: effects of Panax ginseng in type 2 diabetic Goto-Kakizaki rats
Chunxiu Hu, Heng Wei, Hongwei Kong, Jildau Bouwman, Vanessa Gonzalez-Covarrubias, Rob van der Heijden, Theo H. Reijmers, Xu Bao, Elwin R. Verheij, Thomas Hankemeier, Guowang Xu, Jan van der Greef and Mei Wang
08/2011

Elemental Composition determination based on MSn
Miguel-Rojas-Cherto, Piotr T. Kasper, Egon L. Willighagen, Rob Vreeken, Thomas Hankemeier and Theo Reijmers
07/2011

Canonical correlation analysis of multiple sensory directed metabolomics data blocks reveals corresponding parts between data blocks
T.G. Doeswijk, J.A. Hageman, J.A. Westerhuis, Y. Tikunov, A. Bovy, F.A. van Eeuwijk
07/2011

Quantitative profiling of oxylipins via comprehensive LC-MS/MS analysis: Application to patients undergoing cardiac surgery
Katrin Strassburg, Annemarie M.L. Huijbrechts, Kirsten Koortekaas, Jan Lindeman, Theresa L. Pedersen, John W. Newman, Adrie Dane, Ruud Berger, Thomas Hankemeier, John van Duynhoven, Eric Kalkhoven, Rob Vreeken
06/2011

Simplivariate Models: Uncovering the Underlying Biology in Functional Genomics Data
Saccenti E, Westerhuis JA, Smilde AK, van der Werf MJ, Hageman JA, Hendriks MMWB
06/2011

Between Metabolite Relationships: an essential aspect of metabolic change
Jeroen J. Jansen, Ewa Szymanska, Huub C.J. Hoefsloot, Doris M. Jacobs, Katrin Strassburg and Age K. Smilde
05/2011

Plasma and Liver Lipidomics Response to an Intervention of Rimonabant in ApoE*3Leiden.CETP Transgenic Mice

C. Hu, H. Wei, A.M. van den Hoek, M. Wang, R. van der Heijden, G. Spijksma, T.H. Reijmers, J. Bouwman, S. Wopereis, L.M. Havekes, E. Verheij, T. Hankemeier, G.W. Xu, J. van der Greef
05/2011

Untargeted metabolite discovery in kinetic data from multi-dose intervention studies
Peters, S., Janssen, H.-G., Vivó-Truyols, G
05/2011

Procyanidins in fruit from Sour cherry (Prunus cerasus) differ strongly in chainlength from those in Laurel cherry (Prunus lauracerasus) and Cornelian cherry (Cornus mas)

Capanoglu, E., Boyacioglu, D., De Vos, R.C.H., Hall, R.D., Beekwilder, J.
04/2011

Phaseguides: A paradigm shift in microfluidic priming and emptying
P. Vulto, S. Podszun, P. Meyer, C. Hermann, A. Manz, G. Urban
03/2011

Lab-on-a-chip technologies for massive parallel data generation in the life sciences: a tutorial review
S. Trietsch, H. van der Linden and Th. Hankemeier,
03/2011

New figures of merit for comprehensive functional genomics data: the metabolomics case
Van Batenburg M.F., Coulier L., Van Eeuwijk F., Smilde A.K., and Westerhuis J.A.
03/2011

On the increase of predictive performance with high-level data fusion
Doeswijk T.G., Smilde A.K., Hageman, J.A., Westerhuis J.A. and van Eeuwijk F.A.
03/2011

Crops and tasty, nutrtious food-How can metabolomics help?
Stewart D.W., Shepherd L.V.T., Hall R.D., Fraser P.D.
03/2011

Metabolomics of a model fruit: tomato.
De Vos, R.C.H., Hall, R.D., Moing, A.
03/2011

Plant Metabolomics in a nutshell
Hall, R.D.
03/2011

Biology of plant metabolomics.
Hall, R.D. (Ed.)
03/2011

Discovery of early-stage biomarkers for diabetic kidney disease using MS-based metabolomics (FinnDiane Study)
F. van der Kloet, F. Tempels, N. Ismail, R. van der Heijden, P. Kasper; M. Rojas Cherto, R. van Doorn, G. Spijksma, M. Koek, J. van der Greef, V.P. M„kinen, C. Forsblom, H.Holth”fer, P.H. Groop, T.H. Reijmers, T. Hankemeier
02/2011

Reverse engineering of metabolic networks, a critical assessment
Diana M. Hendrickx, Margriet M. W. B. Hendriks, Paul H. C. Eilers, Age K. Smilde and Huub C. J. Hoefsloot
01/2011

Genome-wide computational function prediction of Arabidopsis thaliana proteins by integration of multiple data sources.
Kourmpetis, Y. A. I., van Dijk, A. D. J., van Ham, R. C. H. J. and ter Braak, C. J. F.
01/2011

Plant Metabolomics and its Potential for Systems Biology Research: Background Concepts, Technology, and Methodology
Allwood J.W., De Vos R.C.H., Moing A., Deborde C., Erban A., Kokpa, J., Goodacre R., Hall, R.D.
01/2011

Measuring plant volatiles.
Verhoeven, H.A., Jonker, H., De Vos, R.C.H., Hall, R.D.
01/2011

Plant metabolomics, Methods and Protocols
Hardy, N.G. & Hall, R.D. (Eds)
01/2011

Extensive metabolic cross-talk in melon fruit revealed by spatial and developmental combinatorial metabolomics
Moing, Annick, Asaph Aharoni, Benoit Biais, Ilana Rogachev, Sagit Meir, Leonid Brodsky, J. William Allwood, Alexander Erban, Warwick B. Dunn, Lorraine Kay, Sjaak de Koning, Ric C.H. de Vos, Harry Jonker, Roland Mumm, Catherine Deborde, Michael Maucourt, St
01/2011

In-vivo D2O labeling in C57Bl/6 mice to quantify static and dynamic changes in cholesterol and cholesterol esters by high resolution LC mass-spectrometry
Castro-Perez JM, Previs SF, McLaren DG, Shah V, Herath K, Bhat G, Johns DG, Wang SP, Mitnaul L, Jensen K, Vreeken R, Hankemeier T, Roddy TP, Hubbard BK
01/2011

Sub-Typing of Rheumatic Diseases Based on a Systems Diagnosis Questionnaire
Herman A. van Wietmarschen, Theo H. Reijmers, Anita J. van der Kooij, Jan Schroen, Heng Wei, Thomas Hankemeier, Jacqueline J. Meulman, Jan van der Greef
01/2011

Polyphenol Identification Based on Systematic and Robust High-Resolution Accurate Mass Spectrometry Fragmentation Analytical Chemistry
J. van der Hooft, J. Vervoort, R. Bino and R. de Vos
12/2010

Gene Regulatory Networks from Multifactorial Perturbations Using Graphical Lasso: Application to the DREAM4 Challenge
Menendez, P., Kourmpetis, Y.A.I., ter Braak, C.J.F., van Eeuwijk, F.A.
12/2010

Human ultra-weak photon emission in relation to the 'Yin/ Yang' concept of Chinese Medicine
Van Wijk R, Van Wijk EPA, Van der Greef, J.
12/2010

Online capillary liquid-liquid electroextraction of peptides as fast pre-concentration prior to LC-MS
Lindenburg PW, Seitzinger R, Tempels FW, Tjaden UR, van der Greef J, Hankemeier T
11/2010

The DNA damage repair protein Ku70 interacts with FOXO4 to coordinate a conserved cellular stress response
Brenkman AB, van den Broek NJ, de Keizer PL, van Gent DC, Burgering BM
11/2010

Depletion zone isotachophoresis, a new micro/nanofluidic electrokinetic method
J. Quist, KGH Janssen, HJ. van der Linden, T. Hankemeier
11/2010

Multi-Stage Elemental Formula Tool for Metabolite Identification
M. Rojas Cherto
11/2010

The Effect of Industrial Food Processing on Potentially Health-Beneficial Tomato Antioxidants
Capanoglu, E. , Beekwilder, Jules , Boyacioglu, Dilek , De Vos, Ric C. H. and Hall, Robert D.
11/2010

Nutrikinetics

Velzen, E. van
11/2010

Chip-based heaterless nano-API-MS
R.-J. Raterink, H. van der Linden and Th. Hankemeier
10/2010

Activation of forkhead box O transcription factors by oncogenic BRAF promotes p21cip1-dependent senescence.
de Keizer PL, Packer LM, Szypowska AA, Riedl-Polderman PE, van den Broek NJ, de Bruin A, Dansen TB, Marais R, Brenkman AB*, Burgering BM
08/2010

Chemometrics in analytical chemistry from an industrial perspective
R. Jellema, S. Krishnan
08/2010

Comparative Transcriptional Profiling and Preliminary Study on Heterosis Mechanism of Super-Hybrid Rice
Song GS, Zhai HL, Peng YG, Zhang L, Wei G, Chen XY, Xiao YG, Wang L, Chen YJ, Wu B, Chen B, Zhang Y, Chen H, Feng XJ, Gong WK, Liu Y, Yin ZJ, Wang F, Liu GZ, Xu HL, Wei XL, Zhao XL, Ouwerkerk PB, Hankemeier T, Reijmers T, Heijden RV, Lu CM, Wang M, Greef JV, Zhu Z.
08/2010

Deconvolution using signal segmentation
R. Jellema, S. Krishnan, M. Hendriks, B. Muilwijk, J. Vogels,
07/2010

Carotenoid and Fatty Acid Metabolism in Light-Stressed Dunaliella salina
Lamers Packo P, Carlien C.W. van de Laak, Petrouchka S. Kaasenbrood, Jeroen Lorier, Marcel Janssen, Ric C.H. De Vos, Raoul J. Bino, Rene H. Wijffels
07/2010

Metabolic profiling of oxylipids at Netherlands Metabolomics Centre
Katrin Strassburg, Annemarie Huijbrechts, Arjan Brenkman, John Newman, Ruud Berger, Thomas Hankemeier, John van Duynhoven, Eric Kalkhoven, Rob Vreeken
06/2010

Micro/nanofluidic preconcentrator for single cell metabolomics
J. Quist, KGH Janssen, HJ. van der Linden, T. Hankemeier
06/2010

An inter-laboratory comparison demonstrates that [H-1]-NMR metabolite fingerprinting is a robust technique for collaborative plant characterization and data collection.
Ward JL, Baker JM, Miller SJ, Deborde C, Maucourt M, Biais B, Rolin D, Moing A, Moco S, Vervoort J, Lommen A, Schafer H, Humpfer E, Beale MH.
06/2010

Metabolite identification pipeline based on MS fragmentation
M. Rojas Cherto
06/2010

Discovery of subtle effects in a human intervention trial through multilevel modeling
C.M. Rubingh, M.J. van Erk, S. Wopereis, T van Vliet, E.R. Verheij, N.H. Cnubbem, B. van Ommen, J. van der Greef and A.K. Smilde
06/2010

Metabolic profiling of oxylipids at Netherlands Metabolomics Centre
Katrin Strassburg, Annemarie Huijbrechts, Arjan Brenkman, John Newman, Ruud Berger, Thomas Hankemeier, John van Duynhoven, Eric Kalkhoven, Rob Vreeken
06/2010

Statistical analysis of the spontaneously emitted photon signals from palm and dorsal sides of both hands in human subjects
Van Wijk EP, Van Wijk R, Bajpai R, Van der Greef J.
06/2010

LC-MS-SPE-NMR for the Isolation and Characterization of neo-Clerodane Diterpenoids from Teucrium luteum subsp flavovirens
Castro A, Moco S, Coll J and Vervoort J.
05/2010

Production of novel antioxidative phenolic amides through heterologous expression of the plant's chlorogenic acid biosynthesis genes in yeast
Moglia A., Cominoa C., Lanteria S., de Vos R., de Waard P., van Beek T.A., Goitred L., Rettad S.F., Beekwilder J.
05/2010

Strategies to optimise the flavonoid content of tomato fruit
Bovy, A.G., Gomez-Roldan, V., Hall, R.D.
04/2010

Comprehensive LC-MS(E) Lipidomic Analysis using a Shotgun Approach and Its Application to Biomarker Detection and Identification in Osteoarthritis Patients
Castro-Perez JM, Kamphorst J, Degroot J, Lafeber F, Goshawk J, Yu K, Shockcor JP, Vreeken RJ, Hankemeier T
03/2010

Stable Single Walled Carbon Nanotube-Streptavidin Complex for Bio-Recognition
Liu ZF., Galli F, Janssen, KGH, Jiang, LH, Van der Linden, HJ, De Geus, DC, Voskamp P, Kuil ME, Olsthoorn RCL, Oosterkamp TH, Hankemeier T, Abrahams JP
03/2010

From QTL to candidate gene: Genetical genomics of simple and complex traits in potato using a pooling strategy
Kloosterman, B., M. Oortwijn, J. uitdeWilligen, T. America, R. de Vos, R.G.F. Visser & C.W.B. Bachem
03/2010

Using ultra-weak photon emission to determine the effect of oligomeric proanthocyanidins on oxidative stress of human skin.
Van Wijk EPA, Van Wijk R, Bosman S.
03/2010

Regulation of Treg functionality by acetylation-mediated Foxp3 protein stabilization
van Loosdregt J, Vercoulen Y, Guichelaar T, Gent YY, Beekman JM, van Beekum O, Brenkman AB, Hijnen DJ, Mutis T, Kalkhoven E, Prakken BJ, Coffer PJ
02/2010

Insight in modulation of inflammation by gene, protein and metabolite profiling in mildly obese males: a human intervention study
M.J. van Erk, S.Wopereis, C.M. Rubingh, T. van Vliet, E.Verheij, N.H.P. Cnubben, T.L. Pedersen, J.W. Newman, A.K. Smilde, J. van der Greef, H.F.J. Hendriks and B. van Ommen
02/2010

Bayesian Markov Random Field Analysis for Protein Function Prediction Based on Network Data
Kourmpetis Y.A.I, van Dijk A.D.J., Bink M.C.A.M., van Ham R.C.H.J., ter Braak C.J.F.
02/2010

Equating or Correction for Between-Block Effects with Application to Body Fluid LC-MS and NMR Metabolomics Data Sets
H. Draisma, T. Reijmers, F. van der Kloet, I. Bobeldijk-Pastorova, E. Spies-Faber, J. Vogels, J. Meulman, D. Boomsma, J. van der Greef, T. Hankemeier
01/2010

Acute and 2-week exposure to prednisolone impair different aspects of beta-cell function in healthy men
Van Raalte D.H., Nofrate V., Bunck M.C., Van Iersel T., Elassaiss Schaap J., Nassander U.K., Heine R.J., Mari A., Dokter W.H., Diamant M.
01/2010

Endocrine pulse identification using penalized methods and a minimum set of assumptions
D.J. Vis, J.A. Westerhuis, H.C.J. Hoefsloot, H. Pijl, F. Roelfsema, J. van der Greef, A.K. Smilde
01/2010

The photographer and the greenhouse: how to analyze plant metabolomics data
J. J. Jansen, S. Smit, H.C.J. Hoefsloot and A.K. Smilde
01/2010

Multivariate paired data analysis: Multilevel PLSDA versus OPLSDA
J.A. Westerhuis, E.J.J. van Velzen, H.C.J. Hoefsloot and A.K. Smilde
01/2010

Dynamic Metabolomics Data Analysis: a Tutorial Review
A.K. Smilde, J.A. Westerhuis, H.C.J. Hoefsloot, S. Bijlsma, C.M. Rubingh, D.J. Vis, R.H. Jellema, H. Pijl, F. Roelfsema and J. van der Greef
01/2010

Plant molecular stress responses face climate change
Ahuja I., R.C.H. De Vos, A.M. Bones & R.D. Hall
01/2010

Biochemical and Molecular Analysis of Pink Tomatoes: Deregulated Expression of the Gene Encoding Transcription Factor S1MYB12 Leads to Pink Tomato Fruit Color
Ballester, A. R., Molthoff, J., de Vos, R C.H., Hekkert, B. T. L., Orzaez, D., Fernandez-Moreno, J. P., Tripodi, P., Grandillo, S., Martin, C., Heldens, J., Ykema, M., Granell, A., Bovy, A.
01/2010

A Role for Differential Glycoconjugation in the Emission of Phenylpropanoid Volatiles from Tomato Fruit Discovered Using a Metabolic Data Fusion Approach
Tikunov, Y. M., de Vos, R. C. H., Paramas, A. M. G., Hall, R. D., Bovy, A. G.
01/2010

Unusual optical properties of collagen and implications for the primo-vascular system.
Van Wijk EPA, Groeneveld M, Van der Greef J, Van Wijk R.
01/2010

Systems Biology-Based Diagnostic Principles as Pillars of the Bridge between Chinese and Western Medicine
Van der Greef J, van Wietmarschen H, Schro
01/2010

The Metabolic Fate of Red Wine and Grape Juice Polyphenols in Humans Assessed by Metabolomics
Dorsten, F. van Grün, C., Velzen, E., van, Jacobs, D., Draijer, R., Duynhoven, J. van
01/2010

The metabolic fate of polyphenols in the human superorganism
Duynhoven, J. van, Vaughan, E., Jacobs, D, Kemperman, R., Velzen, E. van, Gross, G., Roger, R., Possemiers, S., Smilde, A., Doré, J., Westerhuis,J., Wiele T. van de
01/2010

NMR-based metabonomics approaches for the assessment of the metabolic impact of dietary polyphenols on humans (2009Magnetic Resonance in Food Science
Duynhoven, J. van, Velzen, E. van, Gross, G., Dorsten, F. van, Jacobs, D., Bingham, M. Draijer, R., Mulder, T., Koning, T., Vaughan, E., Wiele, T van der, Westerhuis, J., Smilde, AS.
01/2010

Food and Nutritional Science Applications of Magnetic Resonance

Duynhoven, J. van
01/2010

Novel Approaches for Analysing Gut Microbes and Dietary Polyphenols, Challenges and Opportunities
Kemperman, R., Bolca, S., Roger, L., Vaughan, E
01/2010

Trend analysis of time-series data: a novel method for untargeted metabolite discovery
Peters, S., Janssen, H., Vivó-Truyols, G.
01/2010

Challenges of molecular nutrition research 6: the nutritional phenotype database to store, share and evaluate nutritional systems biology studies
Ommen,Ben van, Jildau Bouwman, Lars O. Dragsted, Christian A. Drevon, Ruan Elliott, Philip Groot, Jim Kaput, et al.
01/2010

Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) but not PPARalpha serves as a plasma free fatty acid sensor in liver
Sanderson LM, Degenhardt T, Koppen A, Kalkhoven E, Desvergne B, Mller M, Kersten S
12/2009

Reduced expression of ATP7B affected by Wilson disease-causing mutations is rescued by pharmacological folding chaperones 4-phenylbutyrate and curcumin
Peter V. E. van den Berghe, Janneke M. Stapelbroek, Elmar Krieger, Prim de Bie, Stan F. J. van de Graaf, Reinoud E. A. de Groot, Ellen van Beurden, Ellen Spijker, Roderick H. J. Houwen, Ruud Berger, and Leo W. J. Klomp
12/2009

Systems toxicology study of doxorubicin on rats using ultra performance liquid chromatography coupled with mass spectrometry based metabolomics
Wang J, Reijmers T, Chen L, Van Der Heijden R, Wang M, Peng, S, Hankemeier T, Xu G, Van Der Greef J.
12/2009

Characterization of Chinese Liquor Starter, "Daqu", by Flavor Type with H-1 NMR-Based Nontargeted Analysis
Wu XH , Zheng XW , Han BZ, Vervoort J, Nout MJR
12/2009

Crossfit analysis: a novel method to characterize the dynamics of induced plant responses
J.J. Jansen, N.M. van Dam, H.C.J. Hoefsloot and A.K. Smilde
12/2009

Improved cholesterol phenotype analysis by a model describing how lipoprotein lifecycle processes depend on particle size
D.B. van Schalkwijk, B. van Ommen, K. van Bochove, P.C. Rensen, L.M. Havekes, N.C.A. van de Pas, A. de Graaf, H.C.J. Hoefsloot, J. van der Greef and A. Freidig
12/2009

Topical formulation containing natural oligomeric proanthocyanidins (OPCS) reduces UV-induced oxidative stress in skin as assessed by ultra-weak photon emission (UPE)
Van Wijk EP, Bosman S, Achanta G, Van Wijk R.
12/2009

Functional implications of genetic variation in human PPARgamma
Jeninga EH, Gurnell M, Kalkhoven E
10/2009

Nuclear receptor-coregulator interaction profiling identifies TRIP3 as a novel peroxisome proliferator-activated receptor gamma cofactor?
Koppen A, Houtman R, Pijnenburg D, Jeninga EH, Ruijtenbeek R, Kalkhoven E.
10/2009

RNAi-mediated transgenic Tospovirus resistance broken by intraspecies silencing suppressor protein complementation
Hassani-Mehraban A, Brenkman AB, van den Broek NJ, Goldbach R, Kormelink R
10/2009

Metabolomics data exploration guided by prior knowledge
R.A. van den Berg, C.M. Rubingh, J.A. Westerhuis, M.J. van der Werf and A.K. Smilde
10/2009

Integrating functional genomics data using maximum likelihood based simultaneous component analysis
R.A. van den Berg, I. van Mechelen, T.F. Wilderjans, K. van Deun, H.A.L. Kiers and A.K. Smilde
10/2009

Identification of a quality marker of the fermented off-note in coffee by a non-targeted chemometric approach
Lindinger, C, P. Pollien, R.C.H. de Vos, Y. Tikunov, J. A. Hageman, C. Lambot, R. Fumeaux, E. Voirol-Baliguet and I. Blank.
10/2009

Quality and safety of Chinese herbal medicines guided by a systems biology perspective
Jiangshan Wang, Rob van der Heijden, Shannon Spruit, Thomas Hankemeier, Kelvin Chan, Jan van der Greef, Guowang Xu, Mei Wang
10/2009

Systems biology guided by Chinese medicine reveals new markers for sub-typing rheumatoid arthritis patients.
Van Wietmarschen, H., Yuan, K., Lu, C., Gao, P., Wang, J, Xiao, C., Yan, X., Wang, M, Schro
10/2009

Non-Digestible Food Ingredients, Colonic Microbiota and the Impact on Gut Health and Immunity: A Role for Metabolomics
Jacobs, D., Gaudier, E., Duynhoven, J. van, Vaughan, E
10/2009

Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81)
Jeninga EH, Bugge A, Nielsen R, Kersten S, Hamers N, Dani C, Wabitsch M, Berger R, Stunnenberg HG, Mandrup S, Kalkhoven E
09/2009

Analyzing longitudinal microbial metabolomics data
C.M. Rubingh, S. Bijlsma, R.H. Jellema, K.M. Overkamp, M.J. van der Werf, A.K. Smilde
09/2009

Characterizing the precision of mass-spectrometry based metabolic profiling platforms
A.K. Smilde, M.J. van der Werf, C. Kistemaker and J.P. Schaller
09/2009

Analytical strategies in lipidomics and applications in disease biomarker discovery
Hu C., Van der Heijden R., Wang M., Van der Greef J., Hankemeier T., Xu G.
09/2009

Tissue Selectivity in Multiple Endocrine Neoplasia Type 1-Associated Tumorigenesis
Ana Gracanin, Koen M. A. Dreijerink, Rob B. van der Luijt, Cornelis J. M. Lips and Jo W. M. Höppener
08/2009

Exploring the analysis of structured metabolomics data
M. Verouden, J.A. Westerhuis, M.J. van der Werf and A.K. Smilde
08/2009

Developmental, genetic and environmental factors affect the expression of flavonoid genes, enzymes and metabolites in strawberry fruits
Carbone, F., Preuss, A., De Vos, R. C. H., D'Amico, E., Perrotta, G., Bovy, A. G., Martens, S., Rosati, C.
08/2009

The influence of adaptogens on ultraweak biophoton emission: a pilot experiment
Schutgens F.W.G., Neogi P., Van Wijk E.P.A., Van Wijk R., Wikman G., Wiegant F.A.C.
08/2009

Medullary thyroid carcinoma and biomarkers: past, present and future
W. van Veelen, J. W. B. de Groot, D. S. Acton, R. M. W. Hofstra, J. W. M. Hoppener, T. P. Links & C. J. M. Lips
07/2009

Characterization of rhamnosidases from Lactobacillus plantarum and Lactobacillus acidophilus
Jules Beekwilder, Daniela Marcozzi, Samuele Vecchi, Ric de Vos, Patrick Janssen, Christof Francke, Johan van Hylckama Vlieg and Robert D. Hall
06/2009

Systems toxiology study of doxorubicin on rats using ultra performance liquid chromatography coupled with mass spectrometry based metabolomics
Wang, J., Reijmers, T., Chen, L., Van der Hoeve, R., Wang, M., Peng, S., Hankemeier, T., Zu, G., Van der Greef, J.
05/2009

Automated procedure for candidate compound selection in GC-MS metabolomics based on prediction of Kovats retention index
Mihaleva VV, Verhoeven HA, de Vos RC, Hall RD, van Ham RC.
03/2009

Bioconversion of red ginseng saponines in the gastro-intestinal tract in-vitro model studied by high-performance liquid chromatography-high resolution Fourier transform ion cyclotron resonance mass spectrometry
Hongwei Kong, Mei Wang, Koen Venema, Annet Maathuis, Rob van der Heijden, Jan van der Greef , Guowang Xu and Thomas Hankemeier
03/2009

Alkaloid profiling of the Chinese herbal medicine Fuzi by combination of matrix-assisted laser desorption ionization mass spectrometry with liquid chromatography-mass spectrometry 4
Wang, J., van der, Heiden, R., Spijksma, G., Reijmers, T., Wang, M., Xu, G., Hankemeier, T., and van der Greef. J.
03/2009

Improving the analysis of designed studies by combining statistical modelling with study design information
U. Thissen, S.Wopereis, S.A.A. van den Berg, I.Bobeldijk, R. Kleemann, T. Kooistra, K.Willems van Dijk, B. van Ommen and A.K. Smilde
02/2009

Posttranslational modifications of PPAR-gamma: fine-tuning the metabolic master regulator
van Beekum O, Fleskens V, Kalkhoven E.
02/2009

Metabolic network discovery through reverse engineering of metabolome data
T. Cakir, M.M.W.B. Hendriks, J.A. Westerhuis and A.K. Smilde
02/2009

Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes
S. Wopereis, C.M. Rubingh, M.J. van Erk, E.R Verheij, T. van Vliet, N.H.P. Cnubben, A.K Smilde, J. van der Greef, B. van Ommen, and H.F.J. Hendriks
02/2009

More than a grain of rice: the quest for quality
Fitzgerald, M.E., Mccouch, S., Hall, R.D.
02/2009

Biophoton detection and low-intensity light therapy: A potential clinical partnership
Tafur J., Van Wijk E.P.A., Van Wijk R., Mills P.
02/2009

Multiset Data Analysis: ANOVA Simultaneous Component Analysis and Related Methods.
H. C. J. Hoefsloot, D. J. Vis, J. A. Westerhuis, A. K. Smilde, and J. J. Jansen
02/2009

Analytical strategies in lipidomics and applications in disease biomarker discovery.
Hu C, van der Heijden R, Wang M, van der Greef J, Hankemeier T, Xu G
01/2009

Feasibility of electrodialysis as a fast and selective sample preparation method for the profiling of low-abundant peptides in biofluids
Kamphorst JJ, Tjaden UR, van der Heijden R, DeGroot J, van der Greef J, Hankemeier T
01/2009

Mass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research
Scalbert A, Brennan L, Fiehn O, Hankemeier T, Kristal BS, van Ommen B, Pujos-Guillot E, Verheij E, Wishart D, Wopereis S
01/2009

P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma development
Wendy van Veelen , Rob Klompmaker , Martijn Gloerich, Carola J.R. van Gasteren, Eric Kalkhoven, Ruud Berger, Cornelis J.M. Lips, Rene H. Medema, Jo W.M. Hoppener and Dennis S. Acton
01/2009

Analytical error reduction using single point calibration for accurate and precise metabolomic phenotyping
F. van der Kloet, I. Bobeldijk, E. Verheij, R. Jellema,
01/2009

Plant Micrometabolomics: The Analysis of Endogenous Metabolites Present in a Plant Cell or Tissue
Moco S, B Schneider, J Vervoort
01/2009

Regression by L1 regularization of smart contrasts and sums (ROSCAS) beats PLS and elastic net in latent variable model
Ter Braak C. J. F.
01/2009

Fruit-Surface Flavonoid Accumulation in Tomato Is Controlled by a SlMYB12-Regulated Transcriptional Network
Avital Adato, Tali Mandel, Shira Mintz-Oron, Ilya Venger, Dorit Levy, Merav Yativ, Eva Dominguez, Zhonghua Wang, Ric C. H. De Vos, Reinhard Jetter, Lukas Schreiber, Antonio Heredia, Ilana Rogachev, Asaph Aharoni
01/2009

Metabolomic and genetic analyses of flavonol synthesis in Arabidopsis thaliana support the in vivo involvement of leucoanthocyanidin dioxygenase
Ralf Stracke, Ric C. H. De Vos, Lutz Bartelniewoehner, Hirofumi Ishihara, Martin Sagasser, Stefan Martens and Bernd Weisshaar
01/2009

System-wide molecular evidence for phenotypic buffering in Arabidopsis
Jingyuan Fu, Joost J B Keurentjes, Harro Bouwmeester, Twan America, Francel WA Verstappen, Jane L Ward, Michael H Beale, Ric C H De Vos, Martijn Dijkstra, Richard A Scheltema, Frank Johannes, Maarten Koornneef, Dick Vreugdenhil, Rainer Breitling & Ritsert C Jansen
01/2009

The effect of environmental conditions on extracellular protease activity in controlled fermentations of Aspergillus niger
M. Braaksma, A.K. Smilde, M.J. van der Werf and Peter J. Punt
01/2009

Separation and identification of malonyl-ginsenosides in white ginseng using HPLC-LTQ-FTMS
Hongwei Kong, Mei Wang, Rob van der Heijden, Jan van der Greef , Thomas Hankemeier and Guowang Xu
01/2009

Commentary: "A systems view on the future of medicine: Inspiration from Chinese medicine?"
Verpoorte, R., Crommelin, D., Danhof, M., Gilissen, L. J. W. J., Schuitmaker, H., van der Greef, J., and Witkamp, R. F.
01/2009

NMR-based metabonomics approaches for the assessment of the metabolic impact of dietary polyphenols on humans
Duynhoven, J.P.M. van, Velzen, E.J.J. van, Gross, G., Dorsten, F.A. van, Westerhuis, J.A. & Smilde, A.K.
01/2009

Parameter selection for peak alignment in chromatographic sample profiling: objective quality indicators and use of control samples
Peters, S., Velzen, E. van, Janssen, H.G.
01/2009

Phenotyping tea consumers by nutrikinetic analysis of polyphenolic end-metabolites
Velzen, E. van, Westerhuis, J., van Duynhoven, J., van Dorsten, F., Jacobs, D., Gruen, C., Duchateau, G., Vis, D., Smilde, A
01/2009

Multivariate paired data analysis: Multilevel PLSDA versus OPLSDA
Westerhuis J.A., Velzen E.J.J. van, Hoefsloot H.C.J., Smilde A.K.
01/2009

Solution Titration by Wall Deprotonation During Capillary Filling of Silicon Oxide Nanochannels
Janssen KGH, Hoang HT, ,Floris J, De Vries J, Tas NR, Eijkel JCT, Hankemeier T
11/2008

Exploring and exploiting carotenoid accumulation in Dunaliella salina for cell-factory applications
Packo P. Lamers, Marcel Janssen, Ric C.H. De Vos, Raoul J. Bino and Rene H. Wijffels
11/2008

Enrichment of tomato fruit with health-promoting anthocyanins by expression of select transcription factors
Butelli, E., TIitta, L., Georgio, M., Mock, H-P.,Matros, A., Peterek, S., Schijlen, E.G.W.M., Hall, R.D., Bovy, A.G., Martin, C.A.
11/2008

RPLC-FTMS Method for Lipid Profiling of Plasma: Method Validation and Application to p53 mutant Mouse Model
Hu C., VAn Dommelen J., Van der Heijden R., Spijksma G., Reijmers T.H., Wang M., Xu G., Slee E., Lu X., Van der Greef J., Hankemeier T.
10/2008

The peptidyl-isomerase Pin1 regulates p27Kip1 expression through inhibition of FOXO tumorsuppressors.
Brenkman AB, de Keizer PLJ, van den Broek NJF, van der Groep P, van Diest PJ, van der Horst A, Smits AMM, Burgering BMT
09/2008

Lipodomic approach to evaluate rosuvastatin and atorvastatin at various dosages: investigating defferential effects among statins
Bergheanu S.C., Reijmers T., Zwinderman A.H., Bobeldijk I., Ramaker R., Liem A.H., Van der Greef J., Hankemeier T., Jukema J.W.
08/2008

Multilevel data analysis of a cross-over designed human nutritional study
E.J.J. van Velzen, J.A. Westerhuis, J.P.M. van Duynhoven, F.A. van Dorsten, H.C.J. Hoefsloot, D.M. Jacobs, S. Smit, R. Draijer, C.I. Kroner and A.K. Smilde
08/2008

Discriminant Q2 (DQ2) statistic for improved discrimination in PLSDA models
J.A. Westerhuis, E.J.J. van Velzen, H.C.J. Hoefsloot and A.K. Smilde
08/2008

Predicting sub-Golgi localization of type ii membrane proteins
Van Dijk, A. D. J., Bosch, D., ter Braak, C. J. F., van der Krol, A. R. and van Ham, R. C. H. J.
08/2008

Stress-induced biosynthesis of dicaffeoylquinic acids in globe artichoke
Moglia A, Lanteri S, Comino C, Acquadro A, de Vos R, Beekwilder J.
08/2008

The geometry of ASCA
A.K. Smilde, H.C.J. Hoefsloot and J.A. Westerhuis
07/2008

Flavour metabolomics - Holistic versus targeted profiling in flavour research
De Vos, R.C.H., Y. Tikunov, A.G. Bovy & R.D. Hall.
07/2008

Coffee chemometrics as a new concept: Untargeted metabolic profiling of coffee
Lindinger, C., R.C.H De Vos, C. Lambot, P. Pollien, A. Rytz, E. Voirol-Baliguet, R. Fumeaux, F. Robert, C. Yeretzian & I. Blank
07/2008

The impact of the absence of aliphatic glucosinolates on insect herbivory in Arabidopsis.
Beekwilder, J., Van Leeuwen, W., Van Dam, N.M., Bertossi, M., Grandi, V., Mizzi, L., Soloviev, M., Szabados, L., Molthoff, J.W., Schipper, B., Verbocht, H., De Vos, R.C.H., Morandini, P., Aarts, M.G.M., Bovy, A.G.
04/2008

Comprehensive analysis of the metabolome of Pseudomonas putida S12 grown on different carbon sources
Van der Werf MJ, Overkamp KM, Muilwijk B, Koek MM, van der Werff-van der Vat BJ, Jellema RH, Coulier L, Hankemeier T
04/2008

Similarities and differences in lipidomics profiles among healthy monoygotic twin pairs
Draisma H.H.M., Reijmers T.H., Bobeldijk-Pastorova I., Meulman J.J., Estourgie-van Burk G.F., Bartels M., Ramaker R., Van der Greef J., Boomsma D.I., Hankemeier T.
03/2008

Higher mass loadability in GCxGC-MS: improved analytical performance for metabolomics analysis
Koek M, Muilwijk B, Van Stee LLP, Hankemeier T
01/2008

Parafasca: ASCA combined with Parafac for the analysis of metabolic fingerprinting data
J.J. Jansen, R. Bro, H.C.J. Hoefsloot, F.W.J. van den Berg, J.A. Westerhuis and A.K. Smilde
01/2008

Assessment of PLSDA cross validation
J.A. Westerhuis, H.C.J. Hoefsloot, S. Smit, D.J. Vis, A.K. Smilde, E.J.J. van Velzen, J.P.M. van Duijnhoven and F.A. van Dorsten
01/2008

Simplivariate models: ideas and first results
J.A. Hageman, M.M.W.B. Hendriks, J.A. Westerhuis, M.J. van der Werf, R. Berger and A.K. Smilde
01/2008

Predicting and understanding transcription factor interactions based on sequence level determinants of combinatorial control
Van Dijk, A.D.J., ter Braak, C.J.F. Immink, G..H., Angenent, G.C., van Ham, R.C.H.J.
01/2008

Bootstrap Confidence Intervals for Principal Response Curves
Timmerman, M. E. & ter Braak, C. J. F.
01/2008

Plant metabolomics applications in the Brassicaceae: added value for science and industry
Hall, R.D., De Vos, R.C.H., Ward, J.L.
01/2008

Tomato strigolactones are derived from carotenoids and their biosynthesis is promoted by phosphate starvation
Juan Antonio L
01/2008

Accurate mass error correction in liquid chromatography time-of-flight mass spectrometry based metabolomics
Mihaleva, V.V., Vorst, O., Maliepaard, C., Verhoeven, H.A., De Vos, C.H.R., Hall, R.D., van Ham, R.C.H.J.
01/2008

Plant metabolomics and its potential for human nutrition
Hall, R.D., Brouwer, I., Fitzgerald, M.E.
01/2008

Boosting beneficial phytochemicals in vegetable crop plants
Schijlen, E.G.W.M., Beekwilder, J., Hall, R.D., van der Meer, I.M.
01/2008

Changes in Antioxidant and Metabolite Profiles during Production of Tomato Paste
Esra Capanoglu, Jules Beekwilder, Dilek Boyacioglu, Robert Hall and Ric de Vos
01/2008

Antioxidants, Phenolic Compounds, and Nutritional Quality of Different Strawberry Genotypes
Tulipani S, Mezzetti B, Capocasa F, Bompadre S, Beekwilder J, De Vos RCH, Capanoglu E, Bovy A, Battino M.
01/2008

Plant Metabolomics and its potential for human nutrition
Hall, R.D., Brouwer, I., Fitzgerald, M.E.
01/2008

1H NMR metabolite profiling of faeces as a tool to assess the impact of nutrition on the human microbiome
Jacobs, D., Deltimple, N., Velzen, E. van, Bingham, M., Vaughan, E., Bingham, M., Duynhoven, J
01/2008

GC–MS methods for metabolic profiling of microbial fermentation products of dietary polyphenols in human and in vitro intervention studies
Grun, C., Dorsten, F. van, Jacobs, D., Le Belleguic, M., Velzen, E. van, Bingham, M., Janssen, H.G., Duynhoven, J. van
01/2008

Multilevel data analysis of a human nutritional crossover designed study
Velzen, E. van, Westerhuis, J, Duynhoven, J. van Dorsten, F. van, Hoefsloot, H., Smit, S., Draijer, R., Kroner, C.I., Smilde, A.K.
01/2008

Assessment of PLSDA crossvalidation
Westerhuis, J., Hoefsloot, H., Smit, S., Vis, D., Smilde, A., Velzen, E. van, Duynhoven, J. van, Dorsten, F. van
01/2008

The metabolic fate of polyphenols in the human superorganism
J. van Duynhoven, E.E. Vaughan, D. Jacobs, R. Kemperman, E.J.J. van Velzen, G. Gross, L. Roger, S. Possemiers, A.K. Smilde, J. Dore, J.A. Westerhuis and T. van der Wiele
06/2007

Chemical identification strategies by liquid chromatography (LC)-photo diode array (PDA)-solid phase extraction (SPE)-nuclear magnetic resonance (NMR) / mass spectrometry (MS).
Moco S and Vervoort J
01/2007

Production of novel antioxidative phenolic amides through heterologous expression of the plant?s chlorogenic acid biosynthesis genes in yeast
Moglia Andrea, Cinzia Cominoa, Sergio Lanteria, Ric de Vos, Pieter de Waard, Teris A. van Beek, Luca Goitred, Saverio Francesco Rettad, Jules Beekwilder
01/2007

C3?H Isolation and mapping of a C3'H gene (CYP98A49) from globe artichoke, and its expression upon UV-C stress.
Moglia A, Comino C, Portis E, Acquadro A, De Vos RC, Beekwilder J, Lanteri S.
01/2007

In vitro bioconversion of polyphenols from black tea and red wine/grape juice by human intestinal microbiota displays strong inter-individual variability
Gross, G., Jacobs, D., Peters, S., Possemiers, S., van Duynhoven, J., Vaughan, E., Van de Wiele, T
01/2007

Rapid and validated NMR quantification approaches for complex metabolite mixtures
Braganti, B., Peters, S., Jacobs, D., Eymond, T., Klinkenberg, M., Duynhoven, J. van
01/2007

Towards identification of polyphenol metabolites in biofluids by SPE-LC-MS-SPE-NMR
Klinkenberg, M., Roo, N., Alexandre, P., Mahlous, I., Jacobs, D., Janssen, H., Duynhoven, J. van
01/2007

Response of green tea extract on human metabolism at rest and during moderate intensity exercise
Hodgson, A., Randell, R., Fuhrmann, J.C., Rennefahrt, U., Garczarek, U., Jeukendrup, A., Jacobs, D.
01/2007

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