As the central item of the Industrial Biotechnology program, we have chosen to use the metabolomics infrastructure present at TU Delft, TNO, NMC and DSM to study the influence of the extracellular metabolome on the intracellular metabolome and vice versa. As the yeast Saccharomyces is the most widely used microorganism in industrial biotechnology this has been chosen in both projects.
The central topic of the Industrial biotech program, consisting of two PhD projects, is the influence of the extracellular metabolome on the intracellular metabolome and vice versa. At the start of NMC, with its main focus on human applications, two organisations in the Netherlands (TU Delft and TNO) already had a sound track record with respect to metabolomics research in Industrial Biotechnology applications.
Baker’s yeast Saccharomyces cerevisiae is widely used in industrial biotechnology for the production of biofuels, chemicals, and ingredients for the food and feed industry. The production of yeast extracts from baker’s yeast herewith presents an important example. Those yeast extracts are widely being used to generate a ‘meaty’ taste and to strengthen taste in general. This plays an important role in reducing salt content in various foods, i.e.
The Netherlands Metabolomics Centre focusses on the development of metabolomics based technologies and instrumentation to address the current and future challenges in biology, biotechnology and biomedical research in order to improve personalised health and quality of life.